Autodesk Water
Connecting Waterpeople

Using carbonated water in chromatography makes for a greener process, new study finds

  • Using carbonated water in chromatography makes for greener process, new study finds

About the entity

University of Texas Arlington
An educational leader in the heart of the thriving North Texas region, The University of Texas at Arlington nurtures minds within an environment that values excellence, ingenuity, and diversity.

Editors and reviewers of the journal Green Chemistry have highlighted a new study from the University of Texas at Arlington investigating how to make common chemical techniques more environmentally friendly as one of its "hot" articles for 2023.

UTA scientists led by Daniel W. Armstrong, the Welch Distinguished Professor of Chemistry and Biochemistry, found that using carbonated water in chromatography makes this relatively common chemical technique more environmentally benign.

A technique that works by taking a mixture and separating it to examine the individual components, chromatography is widely used to test athletes' urine for performance-enhancing drugs, analyze crime scene evidence such as blood and cloth, test the ingredients in food, or measure the amount of alcohol in drinks, among many other uses. A single chromatograph produces about a liter of liquid waste, with some major pharmaceutical companies operating more than 1,000 chromatographic studies per day.

Using carbonated water in chromatography can reduce the technique's Analytical Method Greenness Score (AMGS). The smaller the score, the more environmentally friendly the process is, Armstrong said.

UTA scientists led by Daniel W. Armstrong, the Welch Distinguished Professor of Chemistry and Biochemistry, found that using carbonated water in chromatography makes this relatively common chemical technique more environmentally benign

"Our research shows that the use of simple carbonated water plus minimal mathematical processing and optimal column geometries produces the lowest AMGS scores yet reported," Armstrong said. "This shows that switching to carbonated liquids instead of other liquids when possible will help make the process of chromatography safer for the environment."

The team also found that using carbonated liquids is just as fast and efficient as other liquids used in chromatography.

"Using 38 amino acids as a test class of molecules, the utility of carbonated liquids as a green alternative was presented at speeds, efficiencies and resolutions never reported," Armstrong said. "Future work will involve applying what we learned regarding carbonated liquids in chromatography to other methodologies, such as mass spectrometry."

This study also corrected the original AMGS equation and extended it to cover more realistic separations including chiral amino acids. The research also noted that this same approach would be useful for NASA, which has special interests in developing lightweight and small instruments for extraterrestrial in situ chiral/achiral chemical analysis.

Subscribe to our newsletter

Topics of interest

The data provided will be treated by iAgua Conocimiento, SL for the purpose of sending emails with updated information and occasionally on products and / or services of interest. For this we need you to check the following box to grant your consent. Remember that at any time you can exercise your rights of access, rectification and elimination of this data. You can consult all the additional and detailed information about Data Protection.